Stereoselective synthesis of the C79–C97 fragment of symbiodinolide

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Stereoselective synthesis of the C79–C97 fragment of symbiodinolide

Symbiodinolide is a polyol marine natural product with a molecular weight of 2860. Herein, a streamlined synthesis of the C79-C97 fragment of symbiodinolide is described. In the synthetic route, a spiroacetalization, a Julia-Kocienski olefination, and a Sharpless asymmetric dihydroxylation were utilized as the key transformations.

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ژورنال

عنوان ژورنال: Beilstein Journal of Organic Chemistry

سال: 2013

ISSN: 1860-5397

DOI: 10.3762/bjoc.9.228